Academics

Interactive “Conquest of Pain” class connects undergrads with leading voices in neurobiology

In a new virtual format, popular course turns to a roster of guest lecturers to share real-world insights

For 20 years, the University of Chicago’s popular "Conquest of Pain" course has given College students a unique opportunity to study the neuroscience and physiologic mechanisms of anesthesia and pain management. Though remote learning changed the hands-on nature of the course this past year, students still were able to take advantage of the seminar format and engage with experts in various fields, from psychologists at NASA to neurosurgeons to scientists studying addiction. 

“The most rewarding part of this class was interacting with a diverse group of world-class physicians and researchers in an intimate setting. Because there were only 18 students in the class, our lectures were highly interactive, and we were able to ask any questions we could think of,” said Emily Guernsey, a third-year majoring in neuroscience and biological sciences. 

With a focus on the pain physiology and proposed mechanisms of anesthesia, the course aims to help undergraduates from all backgrounds understand what causes pain, how it is transmitted and what kinds of treatments are available. Additionally, it highlights anesthesia as one of the most fundamental medical discoveries to date, paving the way for surgery. 

Black and white portrait of Keith Ruskin
Keith Ruskin, professor of anesthesia and critical care

Designed with an emphasis on interaction, the class size was reduced to be taught in an intimate seminar style so that students could ask questions during speakers’ presentations. Typically, students have the chance to shadow Keith Ruskin, professor of anesthesia and critical care, in the operating room to see him care for his patients, as well as explore the post anesthesia care unit, where they can see patients in various states of emergence. They also are able to observe subspecialty procedures like cardiac or neurosurgery. Though the in-person experience was suspended this year due to COVID-19, the visits will resume in time and will be open to any past students who are interested. 

Aspiring to blend both her neuroscience and the biological sciences background, Guernsey eagerly waited to take this class when she entered the College and even wrote her UChicago admissions essay about it. Though there was an abundance of inspiring speakers, she was most impacted by a lecture on chronic pain from Tariq Malik, associate professor of anesthesia and critical care, which emphasized the importance of gaining patient trust and acknowledging the reality of their pain even in the absence of physical evidence.

“Throughout my life, I’ve watched many of my family [members] receive and learn to cope with chronic pain diagnoses. This process is both physically and emotionally draining,” said Guernsey. “I found the lecture inspiring amid the primarily negative discourse surrounding provider-patient interactions in chronic pain treatment.”

To Bryce Millington, a fourth-year majoring in neuroscience, the first day of class was unforgettable. Erin Flynn-Evans, research psychologist and director of the Fatigue Countermeasures Laboratory at NASA’s Ames Research Center, spoke about her sleep physiology studies and how she contributes to the health and well-being of astronauts who do not have the same day and night stimuli in space to help regulate their biological clocks. 

Similarly, fourth-year biological sciences major Ege Yalcindag loved the complexity of the course and its real-life applications. 

“I was able to gain a deep understanding of neurobiological concepts that I had studied only at a surface-level in my biology fundamental courses,” she said “These concepts were grounded in ongoing research trials and real-life patient cases.”

Fourth-year neuroscience major Denisse Morales-Rodriguez enjoyed hearing from Anna Clebone Ruskin, associate professor of anesthesia and critical care, about pediatric anesthesia. 

“I had no idea there were so many different considerations when treating a baby compared to an adult; you can treat an adult with pediatric anesthesia protocols, but not vice versa,” Morales-Rodriguez said. “There is so much still unknown about a baby’s pain physiology and the long-term effects of anesthesia in neonates. It was also fascinating talking to a specialist about her daily work.”

Millington said the class motivated him to work toward improving the current medical procedures and standards as he enters the field.

“With such a large diversity of studies currently happening, I think this class has inspired me to continue to look out for new discoveries and stay up to date on the recent advancements made in the medical field,” he said. “The study of pain is such an interesting field, so I hope to take the different approaches and perspectives on pain that I have learned and apply them when I begin to practice medicine.”

Now in his fifth year of teaching the course, Ruskin said he strives to provide students with a better understanding of the need for pain management in everyday life. 

“The management of pain is a real issue and it's not simple,” he said. “It's not just giving somebody a pill. Pain is a very complex physiologic entity, and the treatment of pain requires a deep understanding not just of what's causing the pain, [but also its neurophysiology], how it's transmitted and how it's processed.”